Not only is the combination not very fruitful, but it can also come with some unpleasant effects. There are a couple of drawbacks that keep physicians from prescribing the two drugs together. Of course, we can’t say that there’s a 100% safe drug (or drug combination) out there. However, the gist here is that these two are considered generally safe to be taken together. Some mixtures of medications can lead to serious and even fatal consequences.
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It is also sometimes prescribed off-label to treat fibromyalgia pain. It is not controlled under the Controlled Substances Act (CSA), either. However, since Flexeril has properties that suppress pain, people may overuse it to amplify those feelings. The activity of Flexeril that depresses the Central Nervous System (CNS) makes it potentially addictive and dangerous.
This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 3 Sep 2023), Cerner Multum™ (updated 28 Aug 2023), ASHP (updated 10 Aug 2023) and others. There is also the possibility of becoming psychologically dependent on Flexeril because of the feelings of relaxation.
Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body. When there is a large level of muscular discomfort, combining a muscle relaxer with ibuprofen is typical. Flexeril can make individuals sleepy throughout the day, so they only take it at night.
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Despite selecting for these low-risk patients, more than 20% of our cohort, regardless of study group, reported poor outcomes at 3 months after the ED visit. Other than the adverse effects listed in Table 4, none occurred in more than 3 participants in any study group. The efficacy of FLEXERIL 5 mg was demonstrated in two seven-day, double-blind, controlled clinical trials enrolling 1405 patients. One study compared FLEXERIL 5 mg and 10 mg t.i.d. to placebo; and a second study compared FLEXERIL 5 mg and 2.5 mg t.i.d. to placebo. Primary endpoints for both trials were determined by patient-generated data and included global impression of change, medication helpfulness, and relief from starting backache. Each endpoint consisted of a score on a 5-point rating scale (from 0 or worst outcome to 4 or best outcome).
I was sucked in by addiction, and with my mind, I kept thinking it was OK because a doctor was prescribing this for me, a doctor was giving me this, a doctor was giving me that. Begin with a free call to an addiction & behavioral health treatment advisor. The We Level Up treatment center network delivers recovery programs that vary by each treatment facility.
RxList does not provide medical advice, diagnosis or treatment. You are encouraged to report negative side effects of prescription drugs to the FDA. Analysis of the data from controlled studies shows that FLEXERIL produces clinical improvement whether or not sedation occurs.
I did drink some alcohol when it was offered to me, and the strangest thing happened. I was sitting on the sofa in the living room, and after some time, I couldn’t move my legs. They didn’t hurt at all, but it was like the connection between my legs and my brain had been severed.
Cyclobenzaprine reduced or abolished skeletal muscle hyperactivity in several animal models. Animal studies indicate that cyclobenzaprine does not act at the neuromuscular junction or directly on skeletal muscle. Evidence suggests that the net effect of cyclobenzaprine is a reduction of tonic somatic motor activity, influencing both gamma (γ) and alpha (α) motor systems. All patients suspected of an overdose with FLEXERIL should receive gastrointestinal decontamination.
Reliance on any information provided by this website is solely at your own risk. So, it’s not unheard of for an orthopedic doctor to co-prescribe both drugs in an attempt to give the patient short-term pain relief. This is a drug that isn’t usually where to buy flexeril considered one of the more common drugs people need to recover from. However, overcoming any addiction can be an incredibly trying process. So, please don’t discount the need for professional treatment if you’re addicted to Flexeril.